L14F (p.Leu14Phe) variant of CYP3A4 (Cytochrome P450 3A4)
L14F (p.Leu14Phe) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data.
L14F (p.Leu14Phe) variant details
- p.Leu14Phe
- cosmic curated COSV60501
- TOPMed rs1815998525
- gnomAD rs1815998525
- Missense
- Variant Prioritization Score for Impact Estimate 0.623
- CADD 9.18
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)