K91Q (p.Lys91Gln) variant of CYP3A4 (Cytochrome P450 3A4)
K91Q (p.Lys91Gln) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
K91Q (p.Lys91Gln) variant details
- p.Lys91Gln
- ExAC rs763972158
- TOPMed rs763972158
- gnomAD rs763972158
- Missense
- Variant Prioritization Score for Impact Estimate 0.605
- CADD 24.30
- PolyPhen-2 0.78
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available