K67R (p.Lys67Arg) variant of CYP3A4 (Cytochrome P450 3A4)
K67R (p.Lys67Arg) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data.
K67R (p.Lys67Arg) variant details
- p.Lys67Arg
- ESP rs140422742
- ExAC rs140422742
- TOPMed rs140422742
- gnomAD rs140422742
- Missense
- Variant Prioritization Score for Impact Estimate 0.542
- CADD 26.50
- PolyPhen-2 0.90
- SIFT 0.03
- Most common in the REMAINING population (allele frequency 0.00023)