K67N (p.Lys67Asn) variant of CYP3A4 (Cytochrome P450 3A4)
K67N (p.Lys67Asn) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data.
K67N (p.Lys67Asn) variant details
- p.Lys67Asn
- ESP rs371184172
- ExAC rs371184172
- TOPMed rs371184172
- gnomAD rs371184172
- Missense
- Variant Prioritization Score for Impact Estimate 0.504
- CADD 22.70
- PolyPhen-2 0.82
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)