K66R (p.Lys66Arg) variant of CYP3A4 (Cytochrome P450 3A4)
K66R (p.Lys66Arg) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data.
K66R (p.Lys66Arg) variant details
- p.Lys66Arg
- TOPMed rs1407019774
- gnomAD rs1407019774
- Missense
- Variant Prioritization Score for Impact Estimate 0.454
- CADD 10.50
- PolyPhen-2 0.02
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 2.4e-05)