K55Q (p.Lys55Gln) variant of CYP3A4 (Cytochrome P450 3A4)
K55Q (p.Lys55Gln) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
K55Q (p.Lys55Gln) variant details
- p.Lys55Gln
- TOPMed rs1210093449
- gnomAD rs1210093449
- Missense
- Variant Prioritization Score for Impact Estimate 0.441
- CADD 0.54
- PolyPhen-2 0.01
- SIFT 0.20
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available