K35R (p.Lys35Arg) variant of CYP3A4 (Cytochrome P450 3A4)
K35R (p.Lys35Arg) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data.
K35R (p.Lys35Arg) variant details
- p.Lys35Arg
- ExAC rs765739949
- gnomAD rs765739949
- Missense
- Variant Prioritization Score for Impact Estimate 0.581
- CADD 22.40
- PolyPhen-2 0.02
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)