K34E (p.Lys34Glu) variant of CYP3A4 (Cytochrome P450 3A4)
K34E (p.Lys34Glu) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data.
K34E (p.Lys34Glu) variant details
- p.Lys34Glu
- ExAC rs750918249
- gnomAD rs750918249
- Missense
- Variant Prioritization Score for Impact Estimate 0.584
- CADD 23.00
- PolyPhen-2 0.04
- SIFT 0.04
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)