K173E (p.Lys173Glu) variant of CYP3A4 (Cytochrome P450 3A4)
K173E (p.Lys173Glu) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
K173E (p.Lys173Glu) variant details
- p.Lys173Glu
- gnomAD rs1396501606
- Missense
- Variant Prioritization Score for Impact Estimate 0.621
- CADD 23.90
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available