K168N (p.Lys168Asn) variant of CYP3A4 (Cytochrome P450 3A4)
K168N (p.Lys168Asn) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
K168N (p.Lys168Asn) variant details
- p.Lys168Asn
- 1000Genomes rs568779023
- ExAC rs568779023
- TOPMed rs568779023
- gnomAD rs568779023
- Missense
- Variant Prioritization Score for Impact Estimate 0.0855
- CADD 4.19
- PolyPhen-2 0.02
- SIFT 0.17
- Most common in the 1KG:STU population (allele frequency 0.01)
- Structural context available