I90V (p.Ile90Val) variant of CYP3A4 (Cytochrome P450 3A4)
I90V (p.Ile90Val) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
I90V (p.Ile90Val) variant details
- p.Ile90Val
- gnomAD rs1265327980
- Missense
- Variant Prioritization Score for Impact Estimate 0.514
- CADD 16.30
- PolyPhen-2 0.03
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available