I90T (p.Ile90Thr) variant of CYP3A4 (Cytochrome P450 3A4)
I90T (p.Ile90Thr) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
I90T (p.Ile90Thr) variant details
- p.Ile90Thr
- TOPMed rs1194211831
- gnomAD rs1194211831
- Missense
- Variant Prioritization Score for Impact Estimate 0.61
- CADD 24.80
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available