I38V (p.Ile38Val) variant of CYP3A4 (Cytochrome P450 3A4)
I38V (p.Ile38Val) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data.
I38V (p.Ile38Val) variant details
- p.Ile38Val
- TOPMed rs1339677129
- gnomAD rs1339677129
- Missense
- Variant Prioritization Score for Impact Estimate 0.441
- CADD 15.90
- PolyPhen-2 0.09
- SIFT 0.10
- Most common in the African/African-American population (allele frequency 2.4e-05)