I148V (p.Ile148Val) variant of CYP3A4 (Cytochrome P450 3A4)
I148V (p.Ile148Val) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
I148V (p.Ile148Val) variant details
- p.Ile148Val
- 1000Genomes rs546282579
- ExAC rs546282579
- gnomAD rs546282579
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- CADD 16.50
- PolyPhen-2 0.01
- SIFT 0.03
- Most common in the 1KG:CDX population (allele frequency 0.0057)
- Structural context available