I120T (p.Ile120Thr) variant of CYP3A4 (Cytochrome P450 3A4)
I120T (p.Ile120Thr) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data.
I120T (p.Ile120Thr) variant details
- p.Ile120Thr
- ESP rs147752776
- ExAC rs147752776
- TOPMed rs147752776
- gnomAD rs147752776
- Missense
- Variant Prioritization Score for Impact Estimate 0.2
- CADD 6.33
- PolyPhen-2 0.02
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)