H30R (p.His30Arg) variant of CYP3A4 (Cytochrome P450 3A4)
H30R (p.His30Arg) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data.
H30R (p.His30Arg) variant details
- p.His30Arg
- gnomAD rs1488928031
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- CADD 16.80
- PolyPhen-2 0.39
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)