H28R (p.His28Arg) variant of CYP3A4 (Cytochrome P450 3A4)
H28R (p.His28Arg) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data.
H28R (p.His28Arg) variant details
- p.His28Arg
- ExAC rs751254421
- gnomAD rs751254421
- Missense
- Variant Prioritization Score for Impact Estimate 0.0826
- CADD 3.84
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the South Asian population (allele frequency 2.3e-05)