G77V (p.Gly77Val) variant of CYP3A4 (Cytochrome P450 3A4)
G77V (p.Gly77Val) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data.
G77V (p.Gly77Val) variant details
- p.Gly77Val
- gnomAD rs1343000941
- Missense
- Variant Prioritization Score for Impact Estimate 0.644
- CADD 24.70
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the East Asian population (allele frequency 0.0002)