G73V (p.Gly73Val) variant of CYP3A4 (Cytochrome P450 3A4)
G73V (p.Gly73Val) in CYP3A4 (Cytochrome P450 3A4) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
G73V (p.Gly73Val) variant details
- p.Gly73Val
- NCI-TCGA TCGA novel
- TOPMed rs1815817451
- gnomAD rs1815817451
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.802
- CADD 34.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available