G69R (p.Gly69Arg) variant of CYP3A4 (Cytochrome P450 3A4)
G69R (p.Gly69Arg) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data.
G69R (p.Gly69Arg) variant details
- p.Gly69Arg
- ExAC rs776743510
- gnomAD rs776743510
- Missense
- Variant Prioritization Score for Impact Estimate 0.774
- CADD 29.20
- PolyPhen-2 0.80
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)