G40E (p.Gly40Glu) variant of CYP3A4 (Cytochrome P450 3A4)
G40E (p.Gly40Glu) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data.
G40E (p.Gly40Glu) variant details
- p.Gly40Glu
- ExAC rs770725289
- TOPMed rs770725289
- gnomAD rs770725289
- Missense
- Variant Prioritization Score for Impact Estimate 0.759
- CADD 23.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)