G167R (p.Gly167Arg) variant of CYP3A4 (Cytochrome P450 3A4)
G167R (p.Gly167Arg) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
G167R (p.Gly167Arg) variant details
- p.Gly167Arg
- ExAC rs753163577
- gnomAD rs753163577
- Missense
- Variant Prioritization Score for Impact Estimate 0.491
- CADD 17.90
- PolyPhen-2 0.65
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available