G167A (p.Gly167Ala) variant of CYP3A4 (Cytochrome P450 3A4)
G167A (p.Gly167Ala) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
G167A (p.Gly167Ala) variant details
- p.Gly167Ala
- ExAC rs767982031
- TOPMed rs767982031
- gnomAD rs767982031
- Missense
- Variant Prioritization Score for Impact Estimate 0.425
- CADD 15.80
- PolyPhen-2 0.48
- SIFT 0.02
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available