G109D (p.Gly109Asp) variant of CYP3A4 (Cytochrome P450 3A4)
G109D (p.Gly109Asp) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data.
G109D (p.Gly109Asp) variant details
- p.Gly109Asp
- TOPMed rs1332595521
- Missense
- Variant Prioritization Score for Impact Estimate 0.545
- CADD 19.40
- PolyPhen-2 0.17
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)