G109C (p.Gly109Cys) variant of CYP3A4 (Cytochrome P450 3A4)
G109C (p.Gly109Cys) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data.
G109C (p.Gly109Cys) variant details
- p.Gly109Cys
- ExAC rs777024826
- TOPMed rs777024826
- gnomAD rs777024826
- Missense
- Variant Prioritization Score for Impact Estimate 0.643
- CADD 23.10
- PolyPhen-2 0.30
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)