E63K (p.Glu63Lys) variant of CYP3A4 (Cytochrome P450 3A4)
E63K (p.Glu63Lys) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data.
E63K (p.Glu63Lys) variant details
- p.Glu63Lys
- ExAC rs752813465
- gnomAD rs752813465
- Missense
- Variant Prioritization Score for Impact Estimate 0.114
- CADD 7.48
- PolyPhen-2 0.03
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 9e-07)