E124G (p.Glu124Gly) variant of CYP3A4 (Cytochrome P450 3A4)
E124G (p.Glu124Gly) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
E124G (p.Glu124Gly) variant details
- p.Glu124Gly
- ExAC rs754927937
- gnomAD rs754927937
- Missense
- Variant Prioritization Score for Impact Estimate 0.619
- CADD 23.60
- PolyPhen-2 0.78
- SIFT 0.02
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available