D6E (p.Asp6Glu) variant of CYP3A4 (Cytochrome P450 3A4)
D6E (p.Asp6Glu) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data.
D6E (p.Asp6Glu) variant details
- p.Asp6Glu
- ESP rs140355261
- TOPMed rs140355261
- Missense
- Variant Prioritization Score for Impact Estimate 0.398
- CADD 2.90
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)