C98Y (p.Cys98Tyr) variant of CYP3A4 (Cytochrome P450 3A4)
C98Y (p.Cys98Tyr) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
C98Y (p.Cys98Tyr) variant details
- p.Cys98Tyr
- ExAC rs775220785
- gnomAD rs775220785
- Missense
- Variant Prioritization Score for Impact Estimate 0.638
- CADD 23.70
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available