C98R (p.Cys98Arg) variant of CYP3A4 (Cytochrome P450 3A4)
C98R (p.Cys98Arg) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
C98R (p.Cys98Arg) variant details
- p.Cys98Arg
- gnomAD rs1289416239
- Missense
- Variant Prioritization Score for Impact Estimate 0.612
- CADD 25.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available