C64S (p.Cys64Ser) variant of CYP3A4 (Cytochrome P450 3A4)
C64S (p.Cys64Ser) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data.
C64S (p.Cys64Ser) variant details
- p.Cys64Ser
- TOPMed rs912646349
- gnomAD rs912646349
- Missense
- Variant Prioritization Score for Impact Estimate 0.434
- CADD 22.00
- PolyPhen-2 0.98
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)