A2G (p.Ala2Gly) variant of CYP3A4 (Cytochrome P450 3A4)
A2G (p.Ala2Gly) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data.
A2G (p.Ala2Gly) variant details
- p.Ala2Gly
- 1000Genomes rs371360704
- ESP rs371360704
- ExAC rs371360704
- TOPMed rs371360704
- Missense
- Variant Prioritization Score for Impact Estimate 0.375
- CADD 7.48
- PolyPhen-2 0.00
- SIFT 0.20
- Most common in the East Asian population (allele frequency 2.5e-05)