A150S (p.Ala150Ser) variant of CYP3A4 (Cytochrome P450 3A4)
A150S (p.Ala150Ser) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
A150S (p.Ala150Ser) variant details
- p.Ala150Ser
- ExAC rs746845845
- TOPMed rs746845845
- gnomAD rs746845845
- Missense
- Variant Prioritization Score for Impact Estimate 0.07
- CADD 1.22
- PolyPhen-2 0.01
- SIFT 0.45
- Most common in the Latino/Admixed American population (allele frequency 6.7e-05)
- Structural context available