G11V (p.Gly11Val) variant of CSRP3 (P50461)
G11V (p.Gly11Val) in CSRP3 (P50461) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
G11V (p.Gly11Val) variant details
- p.Gly11Val
- NCI-TCGA Cosmic COSV9978
- cosmic curated COSV99788
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.588
- REVEL 0.48
- CADD 23.50
- PolyPhen-2 0.29
- SIFT 0.05
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available