Y121S (p.Tyr121Ser) variant of CSF3R (Q99062)
Y121S (p.Tyr121Ser) in CSF3R (Q99062) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
Y121S (p.Tyr121Ser) variant details
- p.Tyr121Ser
- ExAC rs780276211
- gnomAD rs780276211
- Missense
- Variant Prioritization Score for Impact Estimate 0.344
- REVEL 0.24
- CADD 25.30
- PolyPhen-2 0.72
- SIFT 0.03
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00025)
- Structural context available