W105L (p.Trp105Leu) variant of CSF3R (Q99062)
W105L (p.Trp105Leu) in CSF3R (Q99062) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
W105L (p.Trp105Leu) variant details
- p.Trp105Leu
- ExAC rs761711277
- gnomAD rs761711277
- Missense
- Variant Prioritization Score for Impact Estimate 0.519
- REVEL 0.48
- CADD 23.30
- PolyPhen-2 0.27
- SIFT 0.05
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available