V148I (p.Val148Ile) variant of CRMP1 (Q14194)
V148I (p.Val148Ile) in CRMP1 (Q14194) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
V148I (p.Val148Ile) variant details
- p.Val148Ile
- rs1417061818
- cosmic curated COSV10610
- TOPMed rs1417061818
- gnomAD rs1417061818
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- ESM-1b 0.00
- AlphaMissense 0.06
- MetaLR 0.38
- MetaSVM -0.49
- PolyPhen-2 0.00
- SIFT 0.25
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available