S114C (p.Ser114Cys) variant of CRMP1 (Q14194)
S114C (p.Ser114Cys) in CRMP1 (Q14194) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
S114C (p.Ser114Cys) variant details
- p.Ser114Cys
- rs1390300757
- NCI-TCGA Cosmic COSV6148
- cosmic curated COSV61481
- TOPMed rs1390300757
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.566
- ESM-1b 0.84
- AlphaMissense 0.07
- MetaLR 0.63
- MetaSVM -0.04
- PolyPhen-2 0.00
- SIFT 0.15
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available