R63Q (p.Arg63Gln) variant of CRMP1 (Q14194)
R63Q (p.Arg63Gln) in CRMP1 (Q14194) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
R63Q (p.Arg63Gln) variant details
- p.Arg63Gln
- rs373508403
- cosmic curated COSV61480
- NCI-TCGA Cosmic COSV6148
- ESP rs373508403
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.415
- ESM-1b 0.48
- AlphaMissense 0.09
- MetaLR 0.36
- MetaSVM -0.49
- PolyPhen-2 0.02
- SIFT 0.22
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available