R238Q (p.Arg238Gln) variant of CRMP1 (Q14194)
R238Q (p.Arg238Gln) in CRMP1 (Q14194) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.92 / 1. The record also includes population frequency data and structural context.
R238Q (p.Arg238Gln) variant details
- p.Arg238Gln
- rs755012630
- NCI-TCGA Cosmic COSV6147
- cosmic curated COSV61479
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.925
- ESM-1b 1.00
- AlphaMissense 0.88
- MetaLR 0.88
- MetaSVM 1.00
- PolyPhen-2 1.00
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available