L97V (p.Leu97Val) variant of CRMP1 (Q14194)
L97V (p.Leu97Val) in CRMP1 (Q14194) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
L97V (p.Leu97Val) variant details
- p.Leu97Val
- rs766297812
- NCI-TCGA Cosmic COSV6148
- cosmic curated COSV61481
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.596
- ESM-1b 1.00
- AlphaMissense 0.11
- MetaLR 0.64
- MetaSVM 0.07
- PolyPhen-2 0.01
- SIFT 0.29
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available