I242L (p.Ile242Leu) variant of CRMP1 (Q14194)
I242L (p.Ile242Leu) in CRMP1 (Q14194) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes structural context.
I242L (p.Ile242Leu) variant details
- p.Ile242Leu
- NCI-TCGA Cosmic COSV6147
- cosmic curated COSV61479
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.509
- ESM-1b 0.66
- AlphaMissense 0.12
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available