E150K (p.Glu150Lys) variant of CRMP1 (Q14194)
E150K (p.Glu150Lys) in CRMP1 (Q14194) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes structural context.
E150K (p.Glu150Lys) variant details
- p.Glu150Lys
- rs868118770
- NCI-TCGA Cosmic COSV6147
- cosmic curated COSV61478
- Ensembl rs868118770
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.414
- ESM-1b 0.00
- AlphaMissense 0.17
- MetaLR 0.69
- MetaSVM 0.33
- PolyPhen-2 0.03
- SIFT 0.20
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available