D87H (p.Asp87His) variant of CRMP1 (Q14194)
D87H (p.Asp87His) in CRMP1 (Q14194) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
D87H (p.Asp87His) variant details
- p.Asp87His
- NCI-TCGA Cosmic COSV1002
- cosmic curated COSV10027
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.547
- REVEL 0.31
- ESM-1b 1.00
- AlphaMissense 0.97
- CADD 25.50
- PolyPhen-2 0.69
- SIFT 0.01
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available