A265T (p.Ala265Thr) variant of CRMP1 (Q14194)
A265T (p.Ala265Thr) in CRMP1 (Q14194) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
A265T (p.Ala265Thr) variant details
- p.Ala265Thr
- rs1450790289
- NCI-TCGA Cosmic COSV6147
- cosmic curated COSV61478
- TOPMed rs1450790289
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.669
- ESM-1b 0.72
- AlphaMissense 0.07
- MetaLR 0.80
- MetaSVM 0.64
- PolyPhen-2 0.97
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available