P100S (p.Pro100Ser) variant of COL4A4 (Collagen alpha-4(IV) chain)

Name: COL4A4 P100S (p.Pro100Ser) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-19
License: https://catvariant.com/terms-of-use

P100S (p.Pro100Ser) in COL4A4 (Collagen alpha-4(IV) chain) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The record also includes variant effect predictions and structural context.

P100S (p.Pro100Ser) variant details

p.Pro100Ser
NCI-TCGA Cosmic COSV6163
Variant assessed as somatic; moderate impact.
Missense
MetaLR 0.90
MetaSVM 0.92
SIFT 0.02
UniProt: Variant assessed as somatic; moderate impact.
Structural context available