G1080R (p.Gly1080Arg) variant of COL2A1 (Collagen alpha-1(II) chain)

G1080R (p.Gly1080Arg) in COL2A1 (Collagen alpha-1(II) chain) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely pathogenic in the context of Spondyloepiphyseal dysplasia congenita; not provided. The record also includes structural context.

G1080R (p.Gly1080Arg) variant details