P121L (p.Pro121Leu) variant of CDKN1C (P49918)
P121L (p.Pro121Leu) in CDKN1C (P49918) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
P121L (p.Pro121Leu) variant details
- p.Pro121Leu
- gnomAD 11-2884025-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.357
- MetaLR 0.35
- MetaSVM -0.74
- CADD 13.60
- SIFT 0.40
- Population evidence available
- Structural context available
- Literature evidence available