V5M (p.Val5Met) variant of CDK7 (Cyclin-dependent kinase 7)
V5M (p.Val5Met) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
V5M (p.Val5Met) variant details
- p.Val5Met
- 1000Genomes rs193107048
- ExAC rs193107048
- TOPMed rs193107048
- gnomAD rs193107048
- Missense
- Variant Prioritization Score for Impact Estimate 0.374
- REVEL 0.14
- CADD 23.20
- PolyPhen-2 0.00
- SIFT 0.37
- Most common in the 1KG:GBR population (allele frequency 0.0057)
- Structural context available