T25A (p.Thr25Ala) variant of CDK7 (Cyclin-dependent kinase 7)
T25A (p.Thr25Ala) in CDK7 (Cyclin-dependent kinase 7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
T25A (p.Thr25Ala) variant details
- p.Thr25Ala
- ExAC rs762773235
- TOPMed rs762773235
- gnomAD rs762773235
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.22
- CADD 24.00
- PolyPhen-2 0.64
- SIFT 0.11
- Most common in the Latino/Admixed American population (allele frequency 0.00011)
- Structural context available